The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2021
Filed:
Apr. 15, 2020
Applicant:
The Regent of the University of California, Oakland, CA (US);
Inventors:
Freeman Lan, San Francisco, CA (US);
Benjamin Demaree, Berkeley, CA (US);
Iain Clark, San Francisco, CA (US);
Adam R. Abate, Daly City, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12Q 1/6806 (2013.01); C12Q 2565/629 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as 'SiC-seq', which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided.