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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11124781 B1

PDFFull Text
Expired
Date of Patent:
Sep. 21, 2021

Filed:

Jun. 22, 2019

P97-ids fusion proteins

Applicant:

Bioasis Technologies Inc., Guilford, CT (US);

Inventors:

Timothy Z. Vitalis, Vancouver, CA;

Reinhard Gabathuler, Montreal, CA;

Assignee:

Bioasis Technologies, Inc., BC, CA;

Attorneys:

Locke Lord LLP

Nicholas J. DiCeglie, Jr.

Scott D. Wofsy

Primary Examiner:

Karen Cochrane Carlson

Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 9/14 (2006.01); C12N 9/16 (2006.01); A61K 38/40 (2006.01); A61K 38/46 (2006.01); C07K 14/705 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); A61K 38/40 (2013.01); A61K 38/465 (2013.01); C07K 14/70596 (2013.01); C12N 9/16 (2013.01); C12Y 301/06013 (2013.01); C12Y 306/04006 (2013.01); A61K 9/0019 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/43 (2013.01); C07K 2319/50 (2013.01);
Abstract

Provided are fusion proteins between p97 (melanotransferrin) and iduronate-2-sulfatase (IDS), and related compositions and methods of use thereof, for instance, to facilitate delivery of IDS across the blood-brain barrier (BBB) and/or improve its tissue penetration in CNS and/or peripheral tissues, and thereby treat and/or diagnose Hunter Syndrome (Mucopolysaccharidosis type II; MPS II) and related lysosomal storage disorders, including those having a central nervous system (CNS) component.

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Vitalis, Timothy. (2021). P97-ids fusion proteins (U.S. Patent No. 11124781). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11124781

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