The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Apr. 02, 2019
Applicants:

Kelvin Lee, Newark, DE (US);

Xiaolin Zhang, Iselin, NJ (US);

Inventors:

Kelvin Lee, Newark, DE (US);

Xiaolin Zhang, Iselin, NJ (US);

Assignee:

University of Delaware, Newark, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 9/00 (2006.01); C12N 9/88 (2006.01); C12N 15/85 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0682 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12Y 402/99 (2013.01); C12Y 605/01001 (2013.01); C12N 2510/02 (2013.01); C12N 2511/00 (2013.01);
Abstract

The present invention provides a recombinant eukaryotic cell expressing one or more heterologous double strand break (DSB) repair proteins in an amount effective for enhancing DSB repair in the cell. The recombinant eukaryotic cell may express a recombinant product of interest. Also provided are methods for enhancing double strand break (DSB) repair in eukaryotic cells, establishing host cells for production of a recombinant product of interest, producing a recombinant product of interest, improving production of a recombinant product of interest by eukaryotic cells, and/or investigating suitability of eukaryotic cells as host cells for producing a recombinant product of interest.


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