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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11124569 B1

PDFFull Text
Date of Patent:
Sep. 21, 2021

Filed:

Sep. 16, 2016

Methods of reducing liver pd-1-expressing cd8+ t cells using pd-1 fc fusion proteins that bind fc receptors

Applicants:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Emory University, Atlanta, GA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Gordon J. Freeman, Brookline, MA (US);

Rafi Ahmed, Atlanta, GA (US);

Arlene H. Sharpe, Brookline, MA (US);

Masao Hashimoto, Decatur, GA (US);

Hyun T. Jin, Atlanta, GA (US);

Assignees:

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

President And Fellows Of Harvard College, Cambridge, MA (US);

Emory University, Atlanta, GA (US);

Attorney:

Foley Hoag LLP

Primary Examiner:

Ilia I Ouspenski

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 14/705 (2006.01); A61P 1/16 (2006.01); A61P 35/00 (2006.01); A61K 41/00 (2020.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 41/0038 (2013.01); A61P 1/16 (2018.01); A61P 35/00 (2018.01); C07K 14/70503 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); A61K 2039/572 (2013.01); C07K 2317/73 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors, as well as diagnostic, prognostic, therapeutic methods and compositions related thereto.

Find Patent Forward Citations

Freeman, Gordon. (2021). Methods of reducing liver pd-1-expressing cd8+ t cells using pd-1 fc fusion proteins that bind fc receptors (U.S. Patent No. 11124569). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11124569

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