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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11124520 B1

PDFFull Text
Expired
Date of Patent:
Sep. 21, 2021

Filed:

Dec. 04, 2019

Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibitor and antitumor agents

Applicant:

Duquesne University of the Holy Spirit, Pittsburgh, PA (US);

Inventor:

Aleem Gangjee, Allison Park, PA (US);

Assignee:

Duquesne University of the Holy Spirit, Pittsburgh, PA (US);

Attorneys:

Buchanan Ingersoll & Rooney PC

Craig G. Cochenour, Esq.

Primary Examiner:

Samira J Jean-Louis

Int. Cl.
CPC ...
C07D 487/00 (2006.01); C07D 487/04 (2006.01); C07D 239/42 (2006.01); C07D 239/70 (2006.01); C07D 405/12 (2006.01); C07D 239/94 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 239/42 (2013.01); C07D 239/70 (2013.01); C07D 239/94 (2013.01); C07D 405/12 (2013.01); C07D 487/00 (2013.01);
Abstract

The present invention provides a compound of Formula III, and salts thereof, and a pharmaceutical composition comprising a compound of Formula III: wherein Ris selected from the group consisting of: whereinRis H or an alkyl group having from one to ten carbon atoms; Ris H or an alkyl group having from one to ten carbon atoms; and Ris H or an alkyl group having from one to ten carbon atoms. Methods of treating a patient with cancer with these compounds are also provided.

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Gangjee, Aleem. (2021). Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibitor and antitumor agents (U.S. Patent No. 11124520). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11124520

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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