The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Mar. 02, 2020
Applicant:

Dynavax Technologies Corporation, Emeryville, CA (US);

Inventors:

Stewart D. Chipman, Bainbridge Island, WA (US);

Radwan Kiwan, Richmond, CA (US);

Melissa A. Kachura, Berkeley, CA (US);

Robert Coffman, Portola Valley, CA (US);

Assignee:

DYNAVAX TECHNOLOGIES CORPORATION, Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 31/00 (2018.01); A61P 35/00 (2018.01);
Abstract

Disclosed are alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, as Toll-like receptor-7 and -8 agonists for enhancing immune responses. Also provided are methods of making pharmaceutical compositions containing these compounds. The present disclosure also describes methods of use for the alkyl chain modified 1H-imidazoquinoline compounds, derivatives and analogs thereof, and pharmaceutical compositions containing these compounds for the treatment of disease in a subject.


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