The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Mar. 29, 2018
Applicants:

Jia Zhou, Galveston, TX (US);

Zhiqing Liu, Galveston, TX (US);

NA YE, Galveston, TX (US);

Fang Mei, Galveston, TX (US);

Xiaodong Cheng, Galveston, TX (US);

Inventors:

Jia Zhou, Galveston, TX (US);

Zhiqing Liu, Galveston, TX (US);

Na Ye, Galveston, TX (US);

Fang Mei, Galveston, TX (US);

Xiaodong Cheng, Galveston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/08 (2006.01); C07D 261/20 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01);
U.S. Cl.
CPC ...
C07D 261/08 (2013.01); A61P 31/04 (2018.01); C07D 261/20 (2013.01);
Abstract

Embodiments are directed to a series of novel EPAC antagonists that are designed, synthesized and evaluated in an effort to develop diversified analogues based on the scaffold of the previously identified high-throughput (HTS) hit ESI-09.


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