The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Feb. 10, 2017
Applicant:

Engineered Antigens Inc., Calgary, CA;

Inventors:

Trevor F. Moraes, Toronto, CA;

Christine Chieh-Lin Lai, Toronto, CA;

Yogesh Hooda, Toronto, CA;

Andrew Judd, Mississauga, CA;

Anthony B. Schryvers, Calgary, CA;

Scott D. Gray-Owen, Oakville, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/095 (2006.01); C07K 14/195 (2006.01); C07K 14/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/095 (2013.01); A61K 39/02 (2013.01); C07K 14/195 (2013.01); C07K 14/22 (2013.01); A61K 2039/522 (2013.01); A61K 2039/523 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present disclosure relates to methods for exporting target proteins (e.g., surface lipoproteins) from the cytosol to the extracellular surface of bacterial cells using surface lipoprotein assembly modulator (SLAM) polypeptides. The use of SLAM polypeptides in a method of preparing vaccines useful in the prevention of bacterial infectious diseases is also taught.


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