The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Feb. 04, 2019
Applicants:

Sanofi Pasteur Inc., Swiftwater, PA (US);

SK Bioscience Co., Ltd., Seongnam-si, KR;

Inventors:

Kyungjun An, Seoul, KR;

Dongsoo Ham, Suwon-si, KR;

Hun Kim, Suwon-si, KR;

Sunghyun Kim, Yongin-si, KR;

Jinhwan Shin, Seoul, KR;

Robert Hopfer, Roaring Brook Township, PA (US);

Richard D. Kensinger, Henryville, PA (US);

Moe Kyaw, Swiftwater, PA (US);

Philippe Talaga, Lyons, FR;

Assignees:

SANOFI PASTEUR INC., Swiftwater, PA (US);

SK BIOSCIENCE CO., LTD., Seongnam-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/09 (2006.01); A61K 39/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/092 (2013.01); A61K 9/0019 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/70 (2013.01);
Abstract

Provided are mixed carrier, multivalent pneumococcal conjugate compositions comprising 21 different pneumococcal capsular polysaccharide-protein conjugates, wherein each of the conjugates includes a capsular polysaccharide from a different serotype ofconjugated to either tetanus toxoid (TT) or CRM, wherein theserotypes are selected from 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11 A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F, where the capsular polysaccharides of two of serotypes 1, 3, and 5 and one or both of serotypes 15B and 22F are conjugated to TT and the remaining capsular polysaccharides are conjugated to CRM. Also provided are methods of producing the mixed carrier, multivalent pneumococcal conjugate compositions and methods of using the same for prophylaxis againstinfection or disease in a subject.


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