The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Sep. 04, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Alan S. Verkman, San Francisco, CA (US);

Cristina Esteva-Font, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 31/425 (2006.01); A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 31/425 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/47 (2013.01);
Abstract

Provided herein are compounds that are urea transporter-A inhibitors that are useful for producing a strong diuretic response and may be used for treating refractory edema associated with cardiovascular, renal, and metabolic diseases, disorders, and conditions.


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