The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2021
Filed:
Feb. 03, 2017
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Omid C. Farokhzad, Waban, MA (US);
Jun Wu, Boston, MA (US);
Xi Zhu, Qingdao, CN;
Jinjun Shi, Boston, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Abstract
This disclosure relates to nanoparticles comprising a core comprising a poly(ester amide) polymer comprising a repeating unit of Formula (Ia): and a repeating unit of Formula (Ib): wherein W, W, X, A, X, A, and Xare as described herein, a payload molecule within the core, and a surface layer comprising a targeting ligand that binds or reacts selectively with a receptor on the outside surface of a cell. Methods of making such nanoparticles, and methods of using such nanoparticles as drug delivery vehicles, are also provided.