The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2021

Filed:

Aug. 25, 2016
Applicants:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

The Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Paul A. Dayton, Carrboro, NC (US);

Paul S. Sheeran, Durham, NC (US);

Terry O. Matsunaga, Tucson, AZ (US);

Mark A. Borden, Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 49/22 (2006.01); A61K 49/00 (2006.01); A61K 41/00 (2020.01); B01J 13/02 (2006.01); A61K 47/06 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/51 (2013.01); A61K 9/5123 (2013.01); A61K 9/5192 (2013.01); A61K 41/0028 (2013.01); A61K 47/06 (2013.01); A61K 49/0002 (2013.01); A61K 49/221 (2013.01); A61K 49/223 (2013.01); A61K 49/226 (2013.01); B01J 13/02 (2013.01); A61K 48/00 (2013.01);
Abstract

Acoustically activatable particles having low vaporization energy are disclosed. A particle of material includes a first substance that includes at least one component that has a boiling point below 25° C. at atmospheric pressure. A second substance, different from the first substance, encapsulates the first substance to create the particle. The particle has a core consisting of a liquid and is an activatable phase change agent. The second substance includes a polymeric brush layer to prevent aggregation and coalescence.


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