The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Mar. 16, 2018
Applicant:

The Penn State Research Foundation, University Park, PA (US);

Inventors:

Scott Eugene Lindner, State College, PA (US);

Susan Hafenstein, Lemont, PA (US);

Assignee:

THE PENN STATE RESEARCH FOUNDATION, University Park, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 23/04 (2018.01); C07K 1/00 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
G01N 23/04 (2013.01); C07K 1/00 (2013.01); C07K 14/47 (2013.01); C07K 2319/23 (2013.01); C07K 2319/50 (2013.01); C07K 2319/80 (2013.01); G01N 2223/612 (2013.01);
Abstract

Provided are processes and materials for solving biological or structural information about proteins or other organic molecules. The processes capitalize on a rigid multimeric nanocage formed from self-assembling substructure proteins. The processes and materials allow for recognition and tight, optionally covalent, bonding of any protein molecule with a tag complementary to a capture sequence on the nanocage. The processes and materials may be used to obtain biological or structural information by cryo-electron microscopy and overcome prior limitations of target protein size or salt concentration.


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