The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Dec. 15, 2016
Applicants:
The Regents of the University of California, Oakland, CA (US);
F. Hoffmann-la Roche Ag, Basel, CH;
Inventors:
Jennifer A. Doudna, Berkeley, CA (US);
Brett T. Staahl, San Francisco, CA (US);
Anirvan Ghosh, San Diego, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12P 21/02 (2006.01); C12N 15/90 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/22 (2013.01); C12N 15/90 (2013.01); C12P 19/34 (2013.01); C12P 21/02 (2013.01); C07K 2319/09 (2013.01); C12N 2310/20 (2017.05);
Abstract
The present disclosure provides modified site-directed modifying polypeptides, and ribonucleoproteins comprising the modified polypeptides. The modified site-directed modifying polypeptides are modified for passive entry into target cells. The modified site-directed modifying polypeptides are useful in a variety of methods for target nucleic acid modification, which methods are also provided.