The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Nov. 16, 2017
Applicant:
Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;
Inventors:
Dan Canaani, Tel Aviv, IL;
Ronni Aram, Tel Aviv, IL;
Iris Dotan, Tel Aviv, IL;
Pnina Gottfried Komlosh, Tel Aviv, IL;
Assignee:
RAMOT AT TEL-AVIV UNIVERSITY LTD., Tel Aviv, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61P 17/02 (2006.01); A61P 35/04 (2006.01); A61K 9/127 (2006.01); C12Q 1/6886 (2018.01); G01N 33/50 (2006.01); G01N 33/52 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 9/127 (2013.01); A61P 17/02 (2018.01); A61P 35/04 (2018.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); G01N 33/502 (2013.01); G01N 33/52 (2013.01); C12N 2310/113 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract
The invention provides modulators of human cancer and tumor metastasis in particular. More specifically the present disclosure relates to modulators of SKAI1BC, an antisense long non-coding RNA which was found to be an epigenetic suppressor of the metastasis suppressor gene KAI1/CD82, compositions, methods and uses thereof for decreasing metastasis, invasion and possibly also proliferation of cancer cells.