The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Feb. 26, 2018
Applicants:

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Eureka Therapeutics, Inc., Emeryville, CA (US);

Inventors:

Katharine Hsu, New York, NY (US);

Nai-Kong V. Cheung, New York, NY (US);

Su Yan, Emeryville, CA (US);

Yiyang Xu, Emeryville, CA (US);

Jingyi Xiang, Emeryville, CA (US);

Cheng Liu, Emeryville, CA (US);

Assignees:

MEMORIAL SLOAN KETTERING CANCER CENTER, New York, NY (US);

EUREKA THERAPEUTICS, INC., Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/295 (2006.01); A61P 35/02 (2006.01); G01N 33/53 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); A61K 47/68 (2017.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/6849 (2017.08); A61P 35/02 (2018.01); C12N 5/10 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); G01N 33/53 (2013.01); C07K 14/70503 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The disclosure provides antibody agents that bind to inhibitory human killer immunoglobulin-like receptors (KIRs). Particular antibody agents of the disclosure include antibody agents that bind to KIR3DL1 (also known as CD158e). Also provided are related nucleic acids, vectors, compositions and methods of using KIR-binding antibody agents of the present technology.


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