The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Mar. 23, 2018
Daegu-gyeongbuk Medical Innovation Foundation, Daegu, KR;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Daegu Gyeongbuk Institute of Science and Technology, Daegu, KR;
Hwan Geun Choi, Seoul, KR;
Eunhwa Ko, Daegu, KR;
Joong-heui Cho, Daegu, KR;
Jung Beom Son, Daegu, KR;
Yi Kyung Ko, Daegu, KR;
Jin-Hee Park, Jeollanam-do, KR;
So Young Kim, Daegu, KR;
Seock Yong Kang, Seoul, KR;
Seungyeon Lee, Daegu, KR;
Hee Yoon Ryu, Daegu, KR;
Nam Doo Kim, Daegu, KR;
Sang Bum Kim, Daegu, KR;
Sun-Hwa Lee, Daegu, KR;
Dayea Kim, Daegu, KR;
Sun Joo Lee, Daegu, KR;
Sungchan Cho, Daejeon, KR;
Kyu-Sun Lee, Daejeon, KR;
Kweon Yu, Daejeon, KR;
Miri Choi, Daejeon, KR;
Ja Wook Koo, Daegu, KR;
Hyang-Sook Hoe, Daegu, KR;
Abstract
The present invention relates to a pyrrolo-pyridine derivative compound, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for the prevention or treatment of protein kinase-related diseases. A compound represented by chemical formula 1, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, according to the present invention, has excellent inhibitory activity against various protein kinases including DYRK1A, and therefore, the pharmaceutical composition containing the same as an active ingredient can be favorably used in the treatment or prevention of protein kinase-related diseases. Particularly, the pharmaceutical composition can be effectively used in the prevention, treatment, or alleviation of Alzheimer's disease, dementia, or Alzheimer's dementia.