The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Apr. 14, 2020
Applicant:

Zhongshan Guanghe Medical Technology Co., Ltd., Guangdong, CN;

Inventors:

Linyong Zhu, Shanghai, CN;

Yujie Hua, Shanghai, CN;

Qiuning Lin, Shanghai, CN;

Yiqing Zhang, Shanghai, CN;

Chunyan Bao, Shanghai, CN;

Xuepeng Zhong, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08F 2/46 (2006.01); C08F 2/50 (2006.01); C08G 61/04 (2006.01); C07D 291/08 (2006.01); A61L 24/00 (2006.01); A61L 24/04 (2006.01); A61L 24/06 (2006.01); A61L 24/08 (2006.01); A61L 26/00 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); A61L 27/20 (2006.01); A61L 27/52 (2006.01); A61L 31/04 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01); C07C 235/12 (2006.01); C08B 37/08 (2006.01); C08F 220/68 (2006.01); C08G 69/10 (2006.01); C08G 73/06 (2006.01); C08J 3/075 (2006.01); C08J 3/28 (2006.01);
U.S. Cl.
CPC ...
C07D 291/08 (2013.01); A61L 24/0031 (2013.01); A61L 24/046 (2013.01); A61L 24/06 (2013.01); A61L 24/08 (2013.01); A61L 26/008 (2013.01); A61L 26/0014 (2013.01); A61L 26/0019 (2013.01); A61L 26/0023 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/20 (2013.01); A61L 27/52 (2013.01); A61L 31/042 (2013.01); A61L 31/048 (2013.01); A61L 31/06 (2013.01); A61L 31/145 (2013.01); C07C 235/12 (2013.01); C08B 37/0072 (2013.01); C08F 220/68 (2013.01); C08G 69/10 (2013.01); C08G 73/06 (2013.01); C08J 3/075 (2013.01); C08J 3/28 (2013.01); C08J 2305/08 (2013.01); C08J 2333/14 (2013.01); C08J 2377/04 (2013.01); C08J 2379/04 (2013.01);
Abstract

This invention provides preparations, compositions, products, and applications of photo-crosslinked hydrogels. Component A—a photosensitive polymer derivative, component B—the photoinitiator, and auxiliary component C—other biocompatible polymer derivative each are respectively dissolved in a biocompatible medium to obtain solution A, solution B, and solution C. The solution A, the solution B, and the optional solution C are mixed homogenously to obtain a hydrogel precursor solution. The hydrogel precursor solution is subject to irradiation of the UV light for photocoupled crosslinking to form a photo-crosslinked hydrogel. The photo-crosslinked hydrogel exhibit rapid speed of photo-curing, strong tissue adhesion, excellent mechanical properties, good biocompatibility, and excellent clinical operability. In addition, this invention also provides a kit for making the photo-crosslinked hydrogel, and applications thereof in tissue engineering, regenerative medicine, 3D printing, and as a carrier of cell, protein, or drug.


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