The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Aug. 23, 2018
Applicant:

Receptos, Llc, New York, NY (US);

Inventors:

Minhua Chen, Suzhou, CN;

Yanfeng Zhang, Suzhou, CN;

Xiaoting Zhai, Suzhou, CN;

Kaiqiang Yan, Suzhou, CN;

Chaohui Yang, Suzhou, CN;

Assignee:

RECEPTOS LLC, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 271/06 (2006.01);
U.S. Cl.
CPC ...
C07D 271/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure is related to crystalline forms of ozanimod hydrochloride, as well as preparation method thereof. The crystalline form of ozanimod hydrochloride provided by the present disclosure can be used for treating autoimmune diseases, particularly multiple sclerosis and ulcerative colitis. The crystalline form of the present disclosure has advantages in at least one aspect of solubility, melting point, stability, dissolution, bioavailability and processability and provides a new and better choice for the preparation of drug product containing ozanimod, and has significant value for drug development.


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