The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Jun. 16, 2019
Jia Zhou, Austin, TX (US);
Allan R. Brasier, Austin, TX (US);
Bing Tian, Austin, TX (US);
Zhiqing Liu, Austin, TX (US);
Haiying Chen, Austin, TX (US);
Erik Rytting, Austin, TX (US);
Jia Zhou, Austin, TX (US);
Allan R. Brasier, Austin, TX (US);
Bing Tian, Austin, TX (US);
Zhiqing Liu, Austin, TX (US);
Haiying Chen, Austin, TX (US);
Erik Rytting, Austin, TX (US);
Board of Regents, The University Of Texas System, Austin, TX (US);
Abstract
Certain embodiments are directed to small molecule selective inhibitors of the BRD4 bromodomain. Compounds described herein can be used to modulate the bronchiolar NFkB-BRD4 axis, which plays a role in acute neutrophilic response to viral molecular patterns. Compounds described herein can be developed as preventive and therapeutic agents for various human diseases and conditions.