The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Feb. 09, 2021
Applicant:
Orphalan S.a., Paris, FR;
Inventors:
Timothy James Morley, Harrogate, GB;
Ronnie Maxwell Lawrence, Upper Gravenhurst, GB;
Naseem Amin, London, GB;
Assignee:
Orphalan S.A., Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 211/14 (2006.01); C07C 209/84 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07C 211/14 (2013.01); C07C 209/84 (2013.01); A61K 9/0053 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention describes a new crystalline form of triethylenetetramine tetrachloride which has improved room temperature stability over known forms and over the dichloride salt. The new crystalline form is characterised by having peaks in an XRPD spectrum at 22.9, 25.4, 25.8, 26.6, 34.6 and 35.3±0.1°2θ and Raman shifts 943, 1173, 1527 and 1612±5 cm. The crystalline form of triethylenetetramine tetrachloride is useful in the treatment of Wilson's disease.