The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Aug. 22, 2018
Applicants:

International Business Machines Corporation, Armonk, NY (US);

Technion Research and Development Foundation Ltd., Haifa, IL;

Inventors:

Govind Kaigala, Rueschlikon, CH;

Federico Paratore, Zurich, CH;

Onur Gökçe, Zurich, CH;

Moran Bercovici, Haifa, IL;

Xander Van Kooten, Boskoop, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 27/447 (2006.01); C07K 1/28 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502746 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); B01L 2200/0673 (2013.01); B01L 2400/0421 (2013.01); C07K 1/28 (2013.01); G01N 27/44773 (2013.01);
Abstract

Embodiments of the invention are directed to a method of separating and encapsulating an analyte on a microfluidic device in order to extract the analyte. A microfluidic device is provided having a main microchannel and a set of one or more auxiliary microchannels, each branching to the main microchannel at respective junctions therewith. A mixture is introduced as a single phase in the main microchannel in order to electrokinetically separate an analyte from the introduced mixture, and in order to confine the separated analyte in a microchannel portion of the main microchannel. The microchannel portion adjoins one of the junctions. One or more encapsulating volumes of an encapsulating phase are injected in the main microchannel via one or more of the auxiliary microchannels. The encapsulating phase is immiscible with said single phase. The encapsulated analyte is extracted from the main microchannel via one or more of the auxiliary microchannels.


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