The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Feb. 14, 2017
Applicant:

Shanghai Jiao Tong University, Shanghai, CN;

Inventors:

Tuo Jin, Shanghai, CN;

Fei Wu, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61M 37/00 (2006.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01); B81C 1/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61M 37/0015 (2013.01); A61K 9/0021 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); B81C 1/00373 (2013.01); A61K 38/00 (2013.01); A61M 2037/0053 (2013.01); B81B 2201/055 (2013.01); B81C 2201/0185 (2013.01);
Abstract

This invention teaches a method to achieve rapid 3D printing of microneedle patches. The 3D printing method comprises a printing nozzle of multiple micro-holes and cold plate/platform on which the microneedle-supporting sheet (membrane) is placed. The solution or aqueous solution of microneedle-forming materials is printed onto the cold microneedle-supporting sheet with programed rate of injection from the nozzle and velocity of the nozzle lifting. The relationship between the injection rate and the lifting velocity determines the shape of the microneedle tips. The freshly printed microneedles on the cold sheet are dried in two ways, drying at a temperature close to the ice point of water or drying after a freeze-thaw treatment of the microneedles.


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