The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Jun. 02, 2018
Applicant:

Etubics Corporation, Seattle, WA (US);

Inventors:

Frank R. Jones, Seattle, WA (US);

Joseph Balint, Seattle, WA (US);

Elizabeth Gabitzsch, Seattle, WA (US);

Assignee:

Etubics Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001106 (2018.08); A61K 39/00117 (2018.08); A61K 39/001152 (2018.08); C07K 16/2827 (2013.01); C12N 15/86 (2013.01); A61K 2039/523 (2013.01); C12N 2710/10343 (2013.01);
Abstract

In certain embodiments, methods and compositions are provided for generating immune responses against tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof. In particular embodiments, there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor antigens such as antigens or epitopes of HER1, HER2/neu, HER3, HER4, or any combination thereof, that allow for vaccinations in individuals with preexisting immunity to adenovirus.


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