The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Jul. 08, 2016
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Nicola Mason, Philadelphia, PA (US);
Daniel J. Powell, Jr., Bala Cynwyd, PA (US);
Mohammed Kazim Panjwani, Philadelphia, PA (US);
Jenessa Smith, San Diego, CA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 39/001124 (2018.08); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 16/2887 (2013.01); C12N 5/0638 (2013.01); A61K 2039/552 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01);
Abstract
The present invention relates to compositions and methods for the treatment of a canine CD20 positive disease or condition using a canine CD20-specific chimeric antigen receptor. One aspect includes a modified canine T cells and pharmaceutical compositions comprising the modified cells for adoptive cell therapy and treating a disease or condition associated with enhanced immunity in canine.