The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Jan. 30, 2017
Applicant:

Oncoceutics, Inc., Philadelphia, PA (US);

Inventors:

Joshua E. Allen, New Haven, CT (US);

Martin Stogniew, Blue Pell, PA (US);

Varun Vijay Prabhu, Philadelphia, PA (US);

Assignee:

Oncoceutics, Inc., Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); C07D 471/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61P 31/04 (2018.01); A61P 35/00 (2018.01); C07D 471/14 (2013.01);
Abstract

Imipridones has been found to selectively modulate Class A G protein-coupled receptors (GPCRs), such as the D2-like subfamily of dopamine receptors, and to be useful for the treatment of conditions and disorders in need of such modulation, such as cancers, psychiatric disorders, and bacterial infections. In addition, methods of identifying whether a subject having these condition, is likely to be responsive to a treatment regimen, such as administration of an imipridone, are provided. Furthermore, methods of assessing the effectiveness of a treatment regimen, such as administration of an imipridone, monitoring, or providing a prognosis for a subject with these condition are also provided.


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