The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2021

Filed:

Jan. 16, 2017
Applicant:

Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;

Inventors:

Yun Lu, Jiangsu, CN;

Xinhua Zhang, Jiangsu, CN;

Daimei Zhang, Jiangsu, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4155 (2006.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 47/36 (2006.01); A61P 7/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4155 (2013.01); A61K 9/20 (2013.01); A61K 9/48 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 9/2095 (2013.01); A61K 9/4833 (2013.01); A61P 7/04 (2018.01);
Abstract

Disclosed is a pharmaceutical composition containing a bicyclo-substituted pyrazolone azo derivative or a salt thereof and a preparation method thereof. In particular, the pharmaceutical composition disclosed in the present invention contains (Z)-5-(2-hydroxyl-3-(2-(3-methyl-5-oxo-1-(5,6,7,8-tetrahydronaphthalene-2-yl)-1H-pyrazol-4(5H)-ylidene)hydrazino)phenyl)furan-2-carboxylic acid or a pharmaceutically acceptable salt thereof, and at least one filler optionally selected from cellulose, microcrystalline cellulose, lactose and starch. The composition has a good stability, dissolution rate and bioavailability, and the preparation process is simple, economical and quick.


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