The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Jun. 06, 2014
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Universite Paul Sabatier Toulouse Iii, Toulouse, FR;
Centre Hospitalier Universitaire DE Toulouse, Toulouse, FR;
Philippe Rouet, Toulouse, FR;
Fatima Smith-Rouet, Toulouse, FR;
Franck Desmoulin, Toulouse, FR;
Michel Galinier, Toulouse, FR;
INSERM (INSTITUTE NATIONAL DE LAS SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
UNIVERSITE PAUL SABATIER TOULOUSE III, Toulouse, FR;
CENTRE HOSPITALIER UNIVEERSITAIRE DE TOULOUSE, Toulouse, FR;
Abstract
The invention is a method for treating a heart failure patient with the steps of measuring the concentration of IGFBP2 in a blood, plasma or urine sample obtained from the heart failure patient and comparing the patient's IGFBP2 level to a threshold value derived from IGFBP2 measured in samples taken from a group of patients with heart failure selected from the group consisting of stage I, stage stage III and stage IV heart failure, according to New York Heart Association (NYHA) classification system. A patient with an IGFBP2 level that exceeds the threshold value is admitted or readmitted to a hospital and treated with at least one treatment selected from the group consisting of administration of a beta-blocker, an angiotensin-converting enzyme inhibitor, an angiotensin receptor blocker, an aldosterone antagonist, an implantable cardiac defibrillator, a cardiac resynchronization therapy, an implantable left ventricular assist device and a heart transplant.