The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Jun. 03, 2015
Euroimmun Medizinische Labordiagnostika Ag, Lübeck, DE;
Lars Komorowski, Ratzeburg, DE;
Madeleine Scharf, Lübeck, DE;
Ramona Miske, Lübeck, DE;
Yvonne Denno, Lübeck, DE;
Inga-Madeleine Dettmann, Ahrensbök, DE;
Christian Probst, Ratzeburg, DE;
Fedor Heidenreich, Hannover, DE;
Ralf Gieß, Hannover, DE;
EUROIMMUN Medizinische Labordiagnostika AG, Lübeck, DE;
Abstract
The present invention relates to a method for diagnosing a disease, comprising the step detecting in a sample an autoantibody binding to the alpha 3 subunit of the human neuronal Na(+)/K(+) ATPase, an isolated and/or recombinant polypeptide comprising the alpha 3 subunit of the human neuronal Na(+)/K(+) ATPase, a use of a membrane-associated human Na(+)/K(+) ATPase or a variant thereof for the diagnosis of a disease, an isolated and/or recombinant polypeptide comprising the alpha 3 subunit of the human neuronal Na(+)/K(+) ATPase or a variant thereof, for use in the treatment of a disease, an autoantibody binding to said polypeptide and a method for isolating such autoantibody, a pharmaceutical composition, medical or diagnostic device or test kit comprising the polypeptide.