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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11112402 B1

PDFFull Text
Date of Patent:
Sep. 07, 2021

Filed:

Oct. 09, 2018

Reagents and methods for detecting pnh type ii white blood cells and their identification as risk factors for thrombotic disorders

Applicant:

Alexion Pharmaceuticals, Inc., Boston, MA (US);

Inventors:

Mayur Movalia, Brewer, ME (US);

Andrea Illingworth, Holden, ME (US);

Susan Faas McKnight, Old Lyme, CT (US);

Russell P. Rother, Oklahoma City, OK (US);

Assignee:

Alexion Pharmaceuticals, Inc., Boston, MA (US);

Attorneys:

Nelson Mullins Riley & Scarborough LLP

Jane E. Remillard, Esq.

Jill Gorny Sloper, Esq.

Primary Examiner:

Lynn Y Fan

Int. Cl.
CPC ...
A61P 7/02 (2006.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01); A61K 31/352 (2006.01); A61K 31/56 (2006.01); A61K 31/727 (2006.01); A61K 35/19 (2015.01); A61K 38/19 (2006.01); A61K 38/48 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5094 (2013.01); A61K 31/352 (2013.01); A61K 31/56 (2013.01); A61K 31/727 (2013.01); A61K 35/19 (2013.01); A61K 38/196 (2013.01); A61K 38/4886 (2013.01); C07K 16/40 (2013.01); G01N 33/56972 (2013.01); G01N 33/6893 (2013.01); G01N 2800/226 (2013.01);
Abstract

The disclosure relates to methods for detecting PNH Type II cell populations in biological samples as well as methods for determining whether a patient is at an increased risk for developing thrombocytopenia or thrombosis based on the percentage of PNH Type II cells in the patient's blood. The disclosure also features reagents and conjugates for use in the methods.

Find Patent Forward Citations

Movalia, Mayur. (2021). Reagents and methods for detecting pnh type ii white blood cells and their identification as risk factors for thrombotic disorders (U.S. Patent No. 11112402). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11112402

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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