The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Aug. 02, 2017
Toyo Kohan Co., Ltd., Tokyo, JP;
Yamaguchi University, Yamaguchi, JP;
Toshiya Tsuda, Yamaguchi, JP;
Shuichi Kamei, Yamaguchi, JP;
Mitsuyoshi Oba, Yamaguchi, JP;
Hirofumi Yamano, Yamaguchi, JP;
Ryouichi Tsunedomi, Yamaguchi, JP;
Shoichi Hazama, Yamaguchi, JP;
Hiroaki Nagano, Yamaguchi, JP;
Toyo Kohan Co., Ltd., Tokyo, JP;
Yamaguchi University, Yamaguchi, JP;
Abstract
In the case of using a blocking nucleic acid to prevent non-specific hybridization of a target nucleic acid with a nucleic acid probe, further excellent efficiency of detecting the target nucleic acid is achieved. A buffer composition used in hybridization of a target nucleic acid with a nucleic acid probe, wherein the buffer composition for hybridization contains a blocking nucleic acid comprising a nucleotide sequence complementary to a region comprising at least a non-detection target nucleotide in a non-target nucleic acid, in a concentration of one or more times higher than the concentration of a nucleic acid in a nucleic acid mixture consisting of the target nucleic acid and the non-target nucleic acid.