The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Feb. 16, 2018
Applicants:

Ajinomoto Co., Inc., Tokyo, JP;

Evolva SA, Reinach, CH;

Inventors:

Markus Schwab, Loerrach, DE;

Maud Babau, Copenhagen, DK;

David Fischer, Arlesheim, CH;

Anaelle Hatsch, Hesingue, FR;

Sabina de Andrade Pereira Tavares, Basel, CH;

Curt Aime Friis Nielsen, Reinach, CH;

Jens Klein, Oberwil, CH;

Corina Daniela Wirdnam, Reinach, CH;

Assignees:

AJINOMOTO CO, INC., Tokyo, JP;

EVOLVA SA, Reinach, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/00 (2006.01); C12N 9/12 (2006.01); C12N 1/16 (2006.01); C12P 1/02 (2006.01); C12P 7/64 (2006.01); C07C 215/10 (2006.01); C07F 9/09 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C12N 1/16 (2013.01); C12N 9/12 (2013.01); C12N 9/1205 (2013.01); C12P 1/02 (2013.01); C12P 7/6481 (2013.01); C12Y 207/01091 (2013.01); C12Y 207/11001 (2013.01); C07C 215/10 (2013.01); C07F 9/09 (2013.01);
Abstract

A method for producing an objective substance such as phytosphingosine and sphinganine using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so that the expression and/or activities of proteins encoded by LCB4 and CKA2 genes are reduced in a culture medium, and collecting the objective substance from cells of the yeast and/or the culture medium.


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