The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Jul. 18, 2017
Fundacion Tecnalia Research & Innovation, Donostia-San Sebastián, ES;
Tomás Roncal Martínez, Donostia-San Sebastián, ES;
Susana Caballero Román, Donostia-San Sebastián, ES;
María Del Mar Díaz De Guereñu Zabarte, Donostia-San Sebastián, ES;
Inés Rincón Arroyo, Donostia-San Sebastián, ES;
Soraya Prieto Fernández, Miñano, ES;
José Ramón Ochoa Gómez, Miñano, ES;
FUNDACION TECNALIA RESEARCH & INNOVATION, Donostia-San Sebastián, ES;
Abstract
The present invention provides a modified strain of the bacteriumobtainable by a method that comprises a step of fusion of two protoplasts from twoparental strains which, compared to the wild type strain offrom which they derive, show: (a) an increased ability to produce acetoin and/or 2,3-butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain ofhas an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3-BDO.