The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Mar. 28, 2018
Applicant:
Cell Design Labs, Inc., Emeryville, CA (US);
Inventors:
Stephen Santoro, Daly City, CA (US);
Scott Coyle, San Francisco, CA (US);
Levi Rupp, San Francisco, CA (US);
Peter Emtage, Lafayette, CA (US);
Assignee:
Cell Design Labs, Inc., Emeryville, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 14/72 (2006.01); A61K 38/17 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); A61K 48/00 (2006.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 38/177 (2013.01); A61K 39/001112 (2018.08); A61K 39/39558 (2013.01); A61K 48/005 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 14/7153 (2013.01); C07K 14/721 (2013.01); C07K 16/2878 (2013.01); C07K 19/00 (2013.01); C12N 5/0637 (2013.01); C12N 5/0646 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/035 (2013.01);
Abstract
Methods and compositions are provided for reversibly localizing proteins to the exterior part of the cell surface. Compositions provided herein can include nucleic acids that encode polypeptides of interest and the ligand binding domain (LBD) of a nuclear hormone receptor. Medical applications are provided, including controlling the toxicity of CAR T cells.