The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Sep. 17, 2019
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Amin Famili, South San Francisco, CA (US);
Germaine Fuh, Pacifica, CA (US);
Patrick Koenig, San Francisco, CA (US);
Chingwei Vivian Lee, Foster City, CA (US);
Karthikan Rajagopal, South San Francisco, CA (US);
Assignee:
Genetech, Inc., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 47/61 (2017.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0048 (2013.01); A61K 9/06 (2013.01); A61K 9/08 (2013.01); A61K 47/61 (2017.08); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention provides antibody conjugates that include antibodies (e.g., anti-VEGF antibodies) covalently linked to polymers (e.g., hyaluronic acid (HA) polymers), cysteine engineered antibodies, pharmaceutical compositions thereof, and uses thereof, for example for treatment of disorders associated with pathological angiogenesis (e.g., ocular disorders).