The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Sep. 27, 2019
H. Lundbeck A/s, Valby, DK;
Jan Torleif Pedersen, Valby, DK;
Kristian Kjaergaard, Valby, DK;
Lars Østergaard Pedersen, Valby, DK;
Ayodeji Abdur-Rasheed Asuni, Valby, DK;
Nina Helen Rosenqvist, Valby, DK;
Justus Claus Alfred Daechsel, Valby, DK;
Karsten Juhl, Greve, DK;
Lena Tagmose, Lyngby, DK;
Mauro Marigo, Skovlunde, DK;
Thomas Jensen, Copenhagen, DK;
Søren Christensen, Valby, DK;
Laurent David, Valby, DK;
Christiane Volbracht, Valby, DK;
Lone Helboe, Valby, DK;
H. Lundbeck A/S, Valby, DK;
Abstract
The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.