The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Feb. 04, 2020
Applicant:
Protagonist Therapeutics, Inc., Newark, CA (US);
Inventors:
Ashok Bhandari, Pleasanton, CA (US);
Dinesh V. Patel, Fremont, CA (US);
Genet Zemede, San Jose, CA (US);
Larry C. Mattheakis, Cupertino, CA (US);
David Liu, Newark, CA (US);
Assignee:
Protagonist Therapeutics, Inc., Newark, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 14/725 (2006.01); C07K 7/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C07K 7/06 (2013.01); C07K 14/7051 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention relates to peptide dimer compounds and peptide monomer compounds that potently inhibit binding of α4β7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, possess high selectivity against α4β1 binding, and have high stability under gastrointestinal conditions.