The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Nov. 01, 2018
Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;
Xiquan Zhang, Lianyungang, CN;
Xingdong Cheng, Lianyungang, CN;
Aiming Zhang, Lianyungang, CN;
Chunguang Xia, Lianyungang, CN;
Lang Chen, Lianyungang, CN;
Ce Gao, Lianyungang, CN;
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., Lianyungang, CN;
Abstract
The present application relates to a method for preparing a cholic acid compound. Specifically, the method prepares a compound as shown in formula I, including subjecting a compound of formula 2 to an oxidization reaction to obtain a compound of formula 3; attaching a trimethylsilyl group to the compound of formula 3 to obtain a compound of formula 4; reacting the compound of formula 4 with acetaldehyde to obtain a compound of formula 5; subjecting the compound of formula 5 to a catalytic hydrogenation reaction to obtain a compound of formula 6; and converting a cyano group of the compound of formula 6 to a carboxyl group to give the compound of formula I.