The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Mar. 22, 2017
Applicants:

Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;

Lianyungang Runzhong Pharmaceutical Co., Ltd., Lianyungang, CN;

Centaurus Biopharma Co., Ltd., Beijing, CN;

Inventors:

Li Zhu, Beijing, CN;

Xiaowei Duan, Beijing, CN;

Liguang Dai, Beijing, CN;

Zhao Yang, Beijing, CN;

Yanqing Yang, Beijing, CN;

Hui Zhang, Beijing, CN;

Yuandong Hu, Beijing, CN;

Yong Peng, Beijing, CN;

Yongxin Han, Beijing, CN;

Rui Zhao, Lianyungang, CN;

Xin Tian, Lianyungang, CN;

Shanchun Wang, Lianyungang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 275/02 (2006.01); A61K 31/425 (2006.01); A61K 31/433 (2006.01); A61P 35/00 (2006.01); C07D 417/14 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 417/04 (2013.01);
Abstract

Provided are a sultam compound having isocitrate dehydrogenase 1 (IDH1) inhibitory activity as represented by formula I or pharmaceutically-acceptable salts, solvates or hydrates thereof, a preparation method thereof, and a pharmaceutical composition containing the compound. The compound or the pharmaceutically-acceptable salts, solvates or hydrates thereof, and the pharmaceutical composition containing the compound can be used to treat IDH1 mutation-induced cancers.


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