The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Jan. 28, 2020
Applicant:
Forma Therapeutics, Inc., Watertown, MA (US);
Inventors:
Kenneth W. Bair, Wellesley, MA (US);
Torsten Herbertz, Stow, MA (US);
Goss S. Kauffman, Ledyard, CT (US);
Katherine J. Kayser-Bricker, Branford, CT (US);
George P. Luke, Clinton, CT (US);
Matthew W. Martin, Arlington, MA (US);
David S. Millan, Watertown, MA (US);
Shawn E. R. Schiller, Haverhill, MA (US);
Adam C. Talbot, Watertown, MA (US);
Assignee:
FORMA Therapeutics, Inc., Watertown, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); A61K 31/4709 (2006.01); A61K 45/06 (2006.01); A61K 31/47 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 215/20 (2006.01); C07D 215/48 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 473/28 (2006.01); C07D 487/04 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/496 (2006.01); A61K 31/501 (2006.01); A61K 31/52 (2006.01); C07D 401/12 (2006.01); C07D 405/04 (2006.01); C07D 417/10 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 215/20 (2013.01); C07D 215/48 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 473/28 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R, R, R, and Rare as described herein.