The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Mar. 13, 2020
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Bolt Biotherapeutics, Inc., Sunnyvale, CA (US);

Inventors:

Michael Nathaniel Alonso, Santa Clara, CA (US);

Edgar George Engleman, Atherton, CA (US);

Shelley Erin Ackerman, Mountain View, CA (US);

Justin Kenkel, Mountain View, CA (US);

Arthur Lee, San Jose, CA (US);

David Y. Jackson, Belmont, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6801 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C07K 16/28 (2013.01); C07K 16/30 (2013.01);
Abstract

The invention provides an immunoconjugate comprising an antibody construct which includes an antigen binding domain and an Fc domain, an adjuvant moiety, and a linker, wherein each adjuvant moiety is covalently bonded to the antibody via the linker. Methods for treating cancer with the immunoconjugates of the invention are also described.


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