The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Nov. 22, 2017
Applicant:

Xin Wen, Alhambra, CA (US);

Inventor:

Xin Wen, Alhambra, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); C12N 9/96 (2006.01); C12N 1/04 (2006.01); A01N 1/02 (2006.01); A61K 38/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A01N 1/0221 (2013.01); A61K 38/28 (2013.01); C12N 1/04 (2013.01); C12N 9/96 (2013.01);
Abstract

Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof, and a method of stabilizing a biologic (e.g., a protein, microbe, cell component or cell) against temperature stress and aggregation. The AFP may be selected from known antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof. The non-antifreeze protein, cell component or cell comprises a known protein, cell component or cell used in the pharmaceutical, medical, agricultural, veterinary and/or food industry(ies). The AFP protects the function of the non-antifreeze protein, microbe(s), cell component(s) or cell(s) under temperature stress (e.g., a temperature of −20-60° C.).


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Wen, Xin. (2021). Composition and method for the protection of proteins, cell components and cells during temperature stress (U.S. Patent No. 11110176). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11110176

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