The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Aug. 05, 2016
Applicants:

Children's Medical Center Corporation, Boston, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Daniel S. Kohane, Newton, MA (US);

Rong Yang, Cambridge, MA (US);

Lily Yun Lin, Austin, TX (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 9/46 (2006.01); A61K 9/06 (2006.01); A61K 31/407 (2006.01); A61K 31/424 (2006.01); A61K 31/431 (2006.01); A61K 31/455 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01); A61K 31/5383 (2006.01); A61K 31/573 (2006.01); A61K 45/06 (2006.01); A61K 47/06 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/20 (2006.01); A61K 47/22 (2006.01); A61P 27/16 (2006.01); A61P 31/04 (2006.01); C08G 79/04 (2006.01); A61K 31/445 (2006.01); A61K 9/00 (2006.01); A61K 38/12 (2006.01); A61K 47/26 (2006.01); C08G 65/335 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/0046 (2013.01); A61K 9/06 (2013.01); A61K 31/407 (2013.01); A61K 31/424 (2013.01); A61K 31/431 (2013.01); A61K 31/445 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/5383 (2013.01); A61K 31/573 (2013.01); A61K 38/12 (2013.01); A61K 45/06 (2013.01); A61K 47/06 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/20 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61P 27/16 (2018.01); A61P 31/04 (2018.01); C08G 65/3355 (2013.01); C08G 79/04 (2013.01);
Abstract

The present invention provides compositions and methods for delivery of therapeutic agents across an barrier. The compositions include a therapeutic agent (e.g., antimicrobial agent, antibiotic, or anesthetic agent), a permeation enhancer which increases the flux of the therapeutic agent across the barrier, and a matrix forming agent. The matrix forming agent forms a gel at a suitable gelation temperature and rheological properties for use in drug delivery, and in some cases, the gelation temperature and rheological properties are not significantly changed from those of the composition without the permeation enhancer. The invention also provides a matrix forming agent and compositions thereof. Such compositions are particularly useful in the treatment of otitis media. Methods of treatment, methods of delivery, and kits for the compositions described herein are also provided.


Find Patent Forward Citations

Kohane, Daniel. (2021). Compositions with permeation enhancers for drug delivery (U.S. Patent No. 11110175). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11110175

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…