The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Jul. 01, 2019
Applicant:
Mercia Pharma, Inc., New York, NY (US);
Inventors:
Peter Blackburn, New York, NY (US);
Stephen Grimes, New York, NY (US);
Assignee:
Mercia Pharma, Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0007 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/57 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6081 (2013.01); C07K 14/4711 (2013.01); Y02A 50/30 (2018.01);
Abstract
A safe and effective vaccine to prevent, slow, halt or reverse progression of Alzheimer's disease in human patients is disclosed. The vaccine includes Aβ1-42 or an beta amyloid self epitope (e.g. Aβ1-15, or other 7-mer or 15-mer peptide epitopes derived from Aβ1-42) conjugated to an immunogenic carrier (e.g. DT) formulated in a water-in-oil Th2-biased adjuvant/delivery system.