The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Sep. 08, 2020
Applicant:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Inventors:
Katherine A. High, Merion Station, PA (US);
Xavier Anguela, Barcelona, ES;
Assignee:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C12N 15/86 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
A61K 38/4846 (2013.01); C12N 9/644 (2013.01); C12N 15/86 (2013.01); C12Y 304/21022 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The invention relates to modified Factor IX coding sequence, expression cassette, vectors such as viral (e.g., lenti- or adeno-associated viral) vectors, and gene transfer methods and uses. In particular, to target Factor IX nucleic acid to cells, tissues or organs for expression (transcription) of Factor IX.