The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Jul. 30, 2018
Applicant:
Rheinische Friedrich-wilhelms-universitaet Bonn, Bonn, DE;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/17 (2015.01); A61P 37/04 (2006.01); A61K 35/33 (2015.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); A61K 35/13 (2015.01); C12N 5/09 (2010.01); A61K 35/12 (2015.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 35/12 (2013.01); A61K 35/13 (2013.01); A61K 35/33 (2013.01); A61K 39/0011 (2013.01); A61P 35/00 (2018.01); A61P 37/04 (2018.01); C07K 14/705 (2013.01); C12N 5/0693 (2013.01); C12N 15/11 (2013.01); A61K 2035/122 (2013.01); A61K 2039/55555 (2013.01); C12N 2501/65 (2013.01); C12N 2502/11 (2013.01); C12N 2502/1157 (2013.01); C12N 2502/1164 (2013.01); C12N 2502/1178 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention pertains to extracellular vesicles (exosomes) that are produced by culturing tumor cells in the presence of various ligands or activators of innate immunity receptors and subsequently isolating and purifying the vesicles in the culture supernatant. The invention provides also pharmaceutical compositions comprising the inventive exosomes. The exosomes of the invention are provided as medicaments for example in the treatment of cancer diseases.