The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2021
Filed:
Oct. 22, 2019
Applicant:
Alps Pharmaceutical Ind. Co., Ltd., Gifu, JP;
Inventors:
Assignee:
ALPS Pharmaceutical Ind. Co., Ltd., Gifu, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7048 (2006.01); A61K 9/28 (2006.01); A61K 47/10 (2017.01); A61K 9/06 (2006.01); A61K 9/08 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 9/06 (2013.01); A61K 9/08 (2013.01); A61K 9/28 (2013.01); A61K 9/4891 (2013.01); A61K 47/10 (2013.01);
Abstract
A water-soluble composition including an O-glycosyl flavonoid compound, L-arginine, a sugar alcohol, and ascorbic acid or an alkali salt of ascorbic acid. The O-glycosyl flavonoid compound is rutin, isoquercitrin, or hesperidin, and a molar ratio between the O-glycosyl flavonoid compound and the sugar alcohol is 1:4.0-12.0. Also provided is a method for making the above-described water-soluble composition by combining the O-glycosyl flavonoid compound, L-arginine, the sugar alcohol, and ascorbic acid or an alkali salt thereof to form a mixture, and heating it at 110° C.-140° C. to melt the mixture.