The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Apr. 04, 2018
Applicant:

Scynexis, Inc., Jersey City, NJ (US);

Inventor:

David A. Angulo Gonzalez, Tampa, FL (US);

Assignee:

Scynexis, Inc., Jersey City, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/506 (2006.01); A61K 31/4439 (2006.01); A61K 31/496 (2006.01); A61K 31/7048 (2006.01); A61P 31/10 (2006.01); A61K 31/4196 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 31/4196 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01); A61P 31/10 (2018.01);
Abstract

The present invention relates to the use of enfumafungin derivative triterpenoid antifungal compounds in combination with other antifungal agents such azoles, polyenes, lipopeptides, and allylamides to treat fungal diseases. More particularly, the invention relates to antifungal combinations of enfumafungin derivative triterpenoids which are inhibitors of (1,3)-β-D-glucan synthesis, in combination with other antifungal agents such as mold-active agents that have activity against molds, including but not limited to voriconazole, isavuconazole, posaconazole, itraconazole and amphotericin B, for the treatment and/or prevention of infections caused by molds.


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