The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2021

Filed:

Nov. 14, 2018
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Dvin Adalian, Pasadena, CA (US);

Samson Chen, Pasadena, CA (US);

Muhammad M. Jilani, Pasadena, CA (US);

Axel Scherer, Pasadena, CA (US);

Xiomara Linnette Madero, Pasadena, CA (US);

Richard Smith, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/1486 (2006.01); A61B 5/145 (2006.01); A61B 5/1473 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14865 (2013.01); A61B 5/1473 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01);
Abstract

Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.


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