The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 2021
Filed:
Jan. 08, 2019
Clearit, Llc, Marblehead, MA (US);
James W. Winkelman, Chestnut Hill, MA (US);
Martin E. Schmieg, Marblehead, MA (US);
ClearIt, LLC, Marblehead, MA (US);
Abstract
Methods and compositions for simulating a dermal compartment of skin are disclosed. In one aspect of the invention, methods of producing such a skin model include the steps of admixing a collagenous protein source, a blood protein source, and dermal cells in an aqueous carrier, and then allowing the resulting mixture to solidify to produce a gel. In one technique, at least a portion of the mixture, e.g., the collagenous protein source is first heated and then cooled to induce gelation. For example, the mixture can be heated to at least 50 degrees C. and then cooled to temperature below 5 degrees C. to induce gelation.